Publications by authors named "M Bojinca"
Article Synopsis
- - Overlap syndrome of systemic sclerosis and idiopathic inflammatory myopathies is becoming more common, but its link with immune-mediated necrotizing myositis is not well-documented, requiring careful differentiation for proper treatment and prognosis.
- - Anti-signal recognition particle (anti-SRP) antibodies are crucial in diagnosing immune-mediated necrotizing myopathy, causing muscle damage and weakness, while their relationship with cardiac issues remains inconclusive, complicating potential management.
- - Diagnosing heart complications like myocarditis in these patients is challenging, often relying on cardiac imaging rather than biopsies, and this paper explores the issues of accurately diagnosing and treating diseases related to collagen and anti-SRP antibodies.
Background/objectives: Psoriasis is a chronic inflammatory condition mediated by the immune system with various manifestations. The increased prevalence of subclinical joint involvement has led to the development of early diagnostic methods for psoriatic arthritis, including several instruments that have been validated and used in clinical practice. The aim of this study was to perform the Romanian translation, cultural adaptation, and validation of three assessment tools: the Early Arthritis for Psoriatic Patients (EARP) Questionnaire, Psoriasis Epidemiology Screening Tool (PEST), and Toronto Psoriatic Arthritis Screen 2 (TOPAS 2), which are designed to evaluate early-stage arthritis in patients with psoriasis.
View Article and Find Full Text PDFPrimary Sjögren's syndrome (pSS) is a complex autoimmune disorder characterized by organ-specific symptoms in the salivary and lacrimal glands, as well as systemic manifestations. Fatigue, a prominent aspect, significantly influences the overall quality of life for individuals with pSS. This review seeks to evaluate the impact of fatigue by exploring its consequences, potential causes, and effects on physical and psychological well-being, while also investigating its management strategies.
View Article and Find Full Text PDFAbout 70% of patients with Sjogren's syndrome suffer from fatigue, and for a large proportion of patients, it is one of the most noticeable manifestations leading to disability. To date, no study has been conducted in Romania to determine the quality of life of patients and the impact of fatigue in patients with Sjogren's syndrome. The present work proposes the translation, cultural adaptation, and validation of two questionnaires for the Romanian context, namely the 'Profile of Fatigue and Discomfort-Sicca Symptoms Inventory' (PROFAD-SSI-SF) and 'Primary Sjogren's Syndrome-Quality of Life' (PSS-QoL), whose purpose is to assess quality of life and fatigue in patients with Sjogren's syndrome.
View Article and Find Full Text PDFArticle Synopsis
- Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the spine, causing lower back pain and stiffness, and can also impact joint health, especially in the hips and knees.
- Treatment options for AS include patient education, exercises, NSAIDs, corticosteroids, and anti-TNF-α biological agents, which significantly improve patient outcomes.
- A case study highlights a 63-year-old patient with AS who developed cerebral tuberculosis after three years on infliximab, raising questions about the safety of continuing biological therapy during AS reactivation.