Publications by authors named "M Boccellino"
Endometriosis is a chronic inflammatory pathology estrogen-dependent. It is a condition affecting 5%-10% of women of reproductive age worldwide. Recent evidence indicating an embryological origin of endometriosis has provided new insights into its pathogenesis and potential therapeutic approaches.
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- - Cancer is a significant global health issue, leading to ongoing research into effective treatments, particularly focusing on natural compounds from plants that may help in prevention and therapy due to their pharmacological benefits.
- - The review evaluates the therapeutic potential of five natural compounds—apigenin, quercetin, piperine, curcumin, and resveratrol—highlighting their anticancer mechanisms, roles in personalized cancer care, and advantages like low toxicity and compatibility with standard treatments.
- - It emphasizes the need for innovative delivery systems and personalized approaches to enhance the effectiveness of these compounds, ultimately supporting a multidisciplinary strategy for improving cancer management and patient outcomes.
Personalized medicine, which involves modifying treatment strategies/drug dosages based on massive laboratory/imaging data, faces large statistical and study design problems. The authors believe that the use of continuous multidimensional data, such as those regarding gut microbiota, or binary multidimensional systems properly transformed into a continuous variable, such as the epigenetic clock, offer an advantageous scenario for the design of trials of personalized medicine. We will discuss examples focusing on kidney diseases, specifically on IgA nephropathy.
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