Publications by authors named "M Blondel"
Mastitis is a major issue for the dairy industry. Despite multiple attempts, the efficacy of available mastitis vaccines is limited and this has been attributed to their incapacity to trigger robust cell-mediated immunity. Yeasts have recently been identified as promising antigen vectors capable of inducing T-cell responses, surpassing the antibody-biased mechanisms elicited by conventional adjuvanted vaccines.
View Article and Find Full Text PDFThe MKK3 module integrates nitrate and light signals to modulate secondary dormancy in .
Proc Natl Acad Sci U S A
October 2024
Seed dormancy corresponds to a reversible blockage of germination. Primary dormancy is established during seed maturation, while secondary dormancy is set up on the dispersed seed, following an exposure to unfavorable factors. Both dormancies are relieved in response to environmental factors, such as light, nitrate, and coldness.
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- Microsatellite instability (MSI), often linked to mismatch repair deficiency in colorectal cancer (CRC), leads to numerous noncoding DNA mutations, particularly affecting RNA splicing sites.
- This research shows that these noncoding mutations happen early in tumor development, even before the cancer cells become mutated in their coding regions, and are associated with altered splicing patterns in mRNA.
- The altered RNA splicing impacts cellular differentiation and promotes the initiation of MSI CRC, indicating that these noncoding changes are significant for cancer progression before traditional coding mutations occur.
Background: Surgical excision is the treatment of choice for feline intracranial meningioma.
Objectives: To report clinical findings, complications, and outcomes following surgery for feline intracranial meningioma.
Methods: Medical records (01/2000-01/2017) of cats that underwent surgical excision of an intracranial meningioma at our institution were reviewed.
Objective: To describe the prevalence of elbow dysplasia (ED) in 13 dog breeds in France.
Animals: A total of 18,870 elbow radiographs taken from 2002 to 2022 were evaluated by 2 independent examiners.
Methods: For each breed, the incidence of each of the 4 International Elbow Working Group scoring classes was extracted from the database.