Capsular types and antibiotic susceptibility of pneumococci isolated from patients in Belgium with serious infections, 1980-1993.

During the 13-year period from 1 November 1980 to 31 January 1993, we received and serotyped a total of 5,619 clinically significant strains of Streptococcus pneumoniae isolated in more than 75 laboratories in Belgium (4,079 [72.6%] were from blood or pleural fluid, 462 [8.2%] were from cerebrospinal fluid, 691 [12.

Capsular types and antibiotic sensitivity of pneumococci isolated from patients with serious infections in Belgium 1980 to 1988.

A total of 2,765 strains of Streptococcus pneumoniae isolated in more than 60 Belgian laboratories from blood or normally sterile body fluids between 1 November 1980 and 31 December 1988 were serotyped. From January 1983 onwards susceptibility of the strains to antimicrobial agents was also tested. The 2,765 isolates belonged to 57 of the 84 currently identified serotypes.

Enoxacin in acute exacerbations of chronic bronchitis: a comparison with amoxycillin.

A total of 43 hospitalized adult patients with acute exacerbations of chronic bronchitis or bronchiectasis due to Gram-negative bacteria were randomized to receive either enoxacin (400 mg bd) or amoxycillin (1,000 mg tid) for 7-12 days. Micro-organisms isolated included 24 Haemophilus influenzae (three beta-lactamases positive), 11 Branhamella catarrhalis (six beta-lactamase positive), two Pseudomonas aeruginosa and two Neisseria meningitidis in 37 evaluable patients. In the enoxacin group (23 patients) 82.

Serotypage Des Pneumocoques (Hemocultures Et Ponctions Tracheales), Sensibilite Aux Antibiotiques Et Considerations Sur L'Usage D'Un Vaccin Specifique.

114 strains isolated by blood cultures and transtracheal aspirations were typed: serotypes 3 and 4 were largely predominant and a 14-valent vaccine (1, 2, 3, 4, 6, 8, 9, 12, 14, 19, 23, 25, 51, 56) should cover 67 % of these strains and protect 53 % of our patients because the efficacy of the vaccine is evaluated at 80 %. A controlled clinical trial seems to be necessary. We did not isolate any penicillin-resistant strain but 14 % of our strains were resistant to tetracycline.