rRNA expansion segment 7 in eukaryotes: from Signature Fold to tentacles.

The ribosomal core is universally conserved across the tree of life. However, eukaryotic ribosomes contain diverse rRNA expansion segments (ESs) on their surfaces. Sites of ES insertions are predicted from sites of insertion of micro-ESs in archaea.

Direct test of the FLRW metric from strongly lensed gravitational wave observations.

The assumptions of large-scale homogeneity and isotropy underly the familiar Friedmann-Lemaître-Robertson-Walker (FLRW) metric that appears to be an accurate description of our Universe. In this paper, we propose a new strategy of testing the validity of the FLRW metric, based on the galactic-scale lensing systems where strongly lensed gravitational waves and their electromagnetic counterparts can be simultaneously detected. Each strong lensing system creates opportunity to infer the curvature parameter of the Universe.

Publisher Correction: Precision cosmology from future lensed gravitational wave and electromagnetic signals.

The original PDF version of this Article inadvertently highlighted the author surnames and omitted the publication date. These have now been corrected in the PDF version of the Article. The HTML version was correct from the time of publication.

Precision cosmology from future lensed gravitational wave and electromagnetic signals.

The standard siren approach of gravitational wave cosmology appeals to the direct luminosity distance estimation through the waveform signals from inspiralling double compact binaries, especially those with electromagnetic counterparts providing redshifts. It is limited by the calibration uncertainties in strain amplitude and relies on the fine details of the waveform. The Einstein telescope is expected to produce 10-10 gravitational wave detections per year, 50-100 of which will be lensed.

Eukaryotic Ribosomal Expansion Segments as Antimicrobial Targets.

Diversity in eukaryotic rRNA structure and function offers possibilities of therapeutic targets. Unlike ribosomes of prokaryotes, eukaryotic ribosomes contain species-specific rRNA expansion segments (ESs) with idiosyncratic structures and functions that are essential and specific to some organisms. Here we investigate expansion segment 7 (ES7), one of the largest and most variable expansions of the eukaryotic ribosome.