Legal regulation of biomedical research: key principles and their implementation.

Objective: Aim: To analyze the key principles underlying the legal regulation of biomedical research and evaluate their practical implementation in contemporary legal frameworks.

Patients And Methods: Materials and Methods: This study employs a comprehensive literature review, including academic publications, legal documents, and international guidelines on biomedical research ethics. Qualitative analysis identified core principles of legal regulation.

Haemophillus influenzae community acquired meningitis occurrence in children despite 10 years vaccination.

Despite of 10 years vaccination of all children within 1st year in Slovakia against H. influenzae, this severe infection still occurs. Among 201 cases of community acquired bacterial meningitis, 14 (7%) were caused by H.

Bacterial meningitis among Roma ethnic minority.

Etiology and risk factors such as malnutrition, diabetes, otitis/sinusitis, alcohol abuse, tuberculosis, low birth weigh as well as mortality and neurologic sequellea in Roma ethnic minority with community acquired bacterial meningitis (CBM) was assessed and compared to all CBM cases.

Bacteremic meningitis is associated with inferior outcome in comparison to community acquired meningitis without bacteremia.

Meningitis associated with bacteremia is rare. Bacteremic form of meningitis occurred in 28 of 201 cases of community acquired meningitis (14%) in Slovakia within last 17 years. Bacteremic meningitis was associated with diabetes (21.