Publications by authors named "M Bickel"
Article Synopsis
- The study analyzes the occurrence, transmission risks, and immune status related to HIV indicator conditions (HIV-ICs) among treatment-naive individuals living with HIV in Germany from 1999 to 2023.
- It includes data from 15,940 diagnoses and found that the majority of participants were male, with a notable incidence rate for syphilis (34 per 1,000 person-years) and high rates for other conditions linked to HIV.
- The findings emphasize the need for targeted screening based on HIV-ICs to identify individuals with weakened immune systems, highlighting the importance of early antiretroviral therapy (ART) initiation.
Article Synopsis
- The study focuses on improving early diagnosis of HIV among individuals with specific conditions known as indicator conditions (ICs), which are associated with higher rates of undiagnosed HIV infections.
- Using data from over 513,000 German healthcare records from 2016 to 2021, the researchers analyzed the HIV prevalence among people with 26 selected ICs, finding notable rates especially in conditions like pneumocystosis and Kaposi's sarcoma.
- The findings indicated significant gender and age disparities, revealing that while many ICs showed high HIV prevalence in younger and middle-aged adults, some female patients had lower prevalence rates in certain conditions compared to males.
Dietary modifications such as caloric restriction (CR) and intermittent fasting (IF) have gained popularity due to their proven health benefits in aged populations. In time restricted feeding (TRF), a form of intermittent fasting, the amount of time for food intake is regulated without restricting the caloric intake. TRF is beneficial for the central nervous system to support brain health in the context of aging.
View Article and Find Full Text PDFIntroduction: Direct-acting antivirals (DAAs) are key to eliminating hepatitis C virus (HCV). In men who have sex with men (MSM) with HIV co-infection, recently acquired HCV infection is common. Sexual practices and reinfection rates may hamper micro-elimination despite high treatment rates.
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- * A 32-year-old woman with multiple sclerosis and immunosuppressed due to medication developed symptoms typical of vaccine-associated yellow fever after vaccination.
- * The use of sofosbuvir as an antiviral treatment helped her recover, highlighting the need for careful patient evaluation before live vaccinations and potential treatment strategies for such cases.