No evidence for sex-differential transcriptomes driving genome-wide sex-differential natural selection.

Sex differences in human transcriptomes have been argued to drive sex-differential selection (SDS). Here, we show that previous evidence supporting this hypothesis has been largely unfounded. We develop a method to test for a genome-wide relationship between sex differences in expression and selection on expression-influencing alleles (expression quantitative trait loci [eQTLs]).

Ground-based simulation of laser link acquisition for inter-satellite laser interferometry.

Laser link acquisition and pointing technique is one of the essential techniques for the inter-satellite laser interferometry for space-based gravitational waves detection and next-generation Earth gravity measurement missions. The first step of building up inter-satellite laser link is using an acquisition camera to capture the inter-satellite laser beam signals within a pre-scanning uncertain cone. Subsequently, high-precision angle measurement technology, namely differential wavefront sensing, is used to achieve a high pointing precision required.

Flavokawain A suppresses the malignant progression of neuroblastoma in vitro depending on inactivation of ERK/VEGF/MMPs signaling pathway.

Background: Neuroblastoma (NB), the most common extracranial solid tumor in children, is featured by high malignancy and poor prognosis. Flavokawain A (FKA), a novel chalcone isolated from the roots of the kava plant, has been identified to exert the tumor-inhibiting properties in various cancers. The present study was formulated to tell about the anticarcinogenic effects of FKA against NB and to thoroughly elucidate the intrinsic molecular mechanisms.

Molecular Copper-Anthraquinone Photocatalysts for Robust Hydrogen Production.

The development of robust and inexpensive photocatalysts for H production under visible light irradiation remains a significant challenge. This study presents a series of square planar copper anthraquinone complexes (RN)CuL (R = ethyl, L = alizarin dianion (CuAA); R = -butyl, L = purpurin dianion (CuPP), (2-hydroxyanthraquinone)formamide dianion (CuAHA)) as molecular photocatalysts to achieve high long-term stability in visible-light-driven H production. These complexes are self-sensitized by the anthraquinone ligands and serve as proton reduction photocatalysts without additional photosensitizers or catalysts.