Publications by authors named "M Besnard"
The RM Press fit cup™: an investigation in 182 hips at ten-year follow-up.
Orthop Traumatol Surg Res
September 2024
Introduction: For over 10 years, the RM Pressfit cup™ has been used in our department. This is a one-piece, elastic, cementless implant designed with standard polyethylene (PE), covered with a thin coating of titanium particles. To date, there is no French study evaluating this cup after more than 10 years.
View Article and Find Full Text PDFPortuguese Results of the ETICC Study: Impact of the Pandemic COVID-19 in the Diagnosis and Management of Colorectal Cancer in 2020 in Portuguese Hospitals.
GE Port J Gastroenterol
August 2024
Introduction: The outbreak of coronavirus disease 2019 (COVID-19) had affected clinical practice in several ways, including the restriction of nonessential endoscopic procedures. Therefore, our aim was to evaluate how colorectal cancer (CRC) diagnosis and management was affected during the first year of pandemics in Portugal.
Methods: This is a Portuguese substudy of the French retrospective multicentric study ETICC ().
Article Synopsis
- Autoimmune polyendocrine syndrome type 1 (APS-1) is a severe genetic disorder resulting from AIRE deficiency, leading to self-reactive T cells causing autoimmune damage in various organs.
- The study investigated the role of interferon-γ in APS-1 by analyzing patient samples and conducting experiments with mice, finding that high levels of interferon-γ correlate with disease activity.
- Treatment with the JAK inhibitor ruxolitinib significantly reduced interferon-γ levels and improved symptoms in APS-1 patients, suggesting that targeting this pathway may be a viable therapeutic approach.
Ameloblasts are specialized epithelial cells in the jaw that have an indispensable role in tooth enamel formation-amelogenesis. Amelogenesis depends on multiple ameloblast-derived proteins that function as a scaffold for hydroxyapatite crystals. The loss of function of ameloblast-derived proteins results in a group of rare congenital disorders called amelogenesis imperfecta.
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- Trochanteric fractures are a significant health concern for the aging population, leading to increased morbidity and mortality, and treatment focuses on promoting independence and reducing complications like postoperative anemia.
- A study was conducted to compare the effects of minimally invasive side plate fixation (MISS™) against conventional fixation (PHS™) in terms of perioperative bleeding and recovery outcomes in patients over 65 with isolated reducible trochanteric fractures.
- Results indicated that MISS significantly reduced perioperative bleeding, operating time, and scar length compared to PHS, suggesting that it may be a more effective surgical option for these patients.