Publications by authors named "M Bertine"
Lenacapavir is the first capsid inhibitor, its use is currently approved for multidrug resistant HIV-1 infection. We report that, despite an initial efficacy of a LEN-containing regimen in patients with multi-drug resistant HIV-2 viruses, virological suppression was not achieved after a year and most patients selected capsid drug-resistance associated mutations.
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- APOBEC3 proteins create some damaged HIV viruses in people who are infected, and this study looked at how these changed when patients switched treatments to dolutegravir and lamivudine.
- Researchers collected blood samples from patients before and after starting the new treatment and found that the number of defective viruses wasn't drastically lower after a year, but more patients had certain mutations related to drug resistance.
- Overall, they noticed changes in the mutations, but more research is needed to see what happens in the long run.
The physiopathological mechanisms responsible for digestive symptoms in COVID-19 patients are still unclear. The aim of this study was to determine the influence of faecal viral shedding on digestive symptoms and propose differential diagnoses in order to understand the gastrointestinal clinical spectrum in acute cases of COVID-19. All patients managed between March and May 2020, from whom stool samples were collected for microbiological investigations, were included.
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- - This study aimed to confirm co-infections of HIV-1 and HIV-2 in West African patients using specialized tests and molecular methods.
- - Conducted from April 2016 to October 2017 in major clinics in Côte d'Ivoire and Burkina Faso, the survey involved 91 patients who underwent various serological and molecular tests for HIV confirmation.
- - Results showed that out of the 91 participants, 75.4% had both HIV-1 and HIV-2, highlighting the need for improved molecular diagnostics to better identify these co-infections in the region.
During pregnancy early third trimester immunization against SARS‐CoV‐2 confers optimal immunity to the neonate.
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