Publications by authors named "M Bernat Albareda"

During the establishment of the symbiosis with legume plants, rhizobia are exposed to hostile physical and chemical microenvironments to which adaptations are required. Stress response proteins including small heat shock proteins (sHSPs) were previously shown to be differentially regulated in bacteroids induced by bv. viciae UPM791 in different hosts.

View Article and Find Full Text PDF

The presence of memory T cell specific for Trypanosoma cruzi in subjects with discordant serology for Chagas disease supports a cleared infection in these subjects. Using high-dimensional flow cytometry, ELISPOT assays and quantitative PCR, antibody-secreting cells and memory B cells specific for T. cruzi, total B-cell phenotypes, innate immune responses and parasite DNA were evaluated in serodiscordant, seropositive and seronegative subjects for T.

View Article and Find Full Text PDF

Cyclophilins (CyPs) are a family of enzymes involved in protein folding. , the causative agent of Chagas disease, has a 19-kDa cyclophilin, CyP19, that was found to be secreted in parasite stages of the CL Brener clone and recognized by sera from -infected mice and patients. The levels of specific antibodies against CyP19 in -infected mice and subjects before and after drug treatment were measured by an in-house enzyme linked immunosorbent assay (ELISA).

View Article and Find Full Text PDF

bv. viciae () UPM791 effectively nodulates pea and lentil, but bacteroids contain a number of proteins differentially expressed depending on the host. One of these host-dependent proteins (C189) is similar to a iminoutyrte-2-oxoglutarate minoransferase (DABA-AT).

View Article and Find Full Text PDF

Background: A drawback in the treatment of chronic Chagas disease (American trypanosomiasis) is the long time required to achieve complete loss of serological reactivity, the standard for determining treatment efficacy.

Methods: Antibody-secreting cells and memory B cells specific for Trypanosoma cruzi and their degree of differentiation were evaluated in adult and pediatric study participants with chronic Chagas disease before and after etiological treatment.

Results: T.

View Article and Find Full Text PDF