Publications by authors named "M Benni"
Donation after circulatory death (DCD) programs are expanding in Europe, in the attempt to expand donors pool. Even in controlled DCD donors, however, a protracted warm ischemia time occurring in the perimortem period might damage organs, making these unsuitable for transplantation. Implementing a strategy of extracorporeal interval support for organ retrieval (EISOR), a regional reperfusion with normothermic, oxygenated blood provides a physiologic environment allowing extensive assessment of potential grafts, and potentially promotes recovery of native function.
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- VV-ECMO is used for severe respiratory failure when traditional ventilation fails, with less focus on circulatory issues compared to VA-ECMO, which is better for circulatory support but worse for respiratory function.
- A case study describes the use of VV-ECMO on a 68-year-old man with acute respiratory failure from massive aspiration, who developed multiple organ failure and was transferred to an ECMO-capable facility.
- The patient showed improvement with VV-ECMO and was eventually discharged after full recovery, highlighting the importance of selecting the right ECMO type based on individual patient needs and conditions.
Even with encouraging recipient outcomes, transplantation using donation after circulatory death (DCD) is still limited. A major barrier to this type of transplantation is the consequences of warm ischemia on graft survival; however, preservation techniques may reduce the consequences of cardiac arrest and provide better organ conservation. Furthermore, DCD in trauma patients could further expand organ donation.
View Article and Find Full Text PDFBackground: This study was conceived to provide systematic data about lung mechanics during early phases of CoVID-19 pneumonia, as long as to explore its variations during prone positioning.
Methods: We enrolled four patients hospitalized in the Intensive Care Unit of "M. Bufalini" hospital, Cesena (Italy); after the positioning of an esophageal balloon, we measured mechanical power, respiratory system and transpulmonary parameters and arterial blood gases every 6 hours, just before decubitus change and 1 hour after prono-supination.