Sickle cell anemia is the world's most common monogenic disease, with a steady rise in the number of cases also in Switzerland. It presents as regenerative anemia and recurrent vaso-occlusive episodes, which can impact all organs. Acute and chronic complications increase morbidity and mortality, significantly reducing life expectancy compared to the general population.
View Article and Find Full Text PDFVenous catheters have become essential devices in the management of hospitalized patients. Indeed, according to several studies, 60 to 70 % of hospitalized patients require venous access during their stay. However, there is a wide range of venous catheters, and it is important to understand their main differences and indications.
View Article and Find Full Text PDFHypernatremia, defined as a serum sodium concentration greater than 145 mmol/l, is an electrolyte disorder associated with increased in-hospital morbidity and mortality. Its prevalence is estimated between 1 to 3% in hospitalized patients and up to 11% in intensive care. It most often results from an impaired thirst mechanism or the inability to access water to drink.
View Article and Find Full Text PDFTaking care of patients in complex situation is a challenge as well in outpatient clinics as in hospital settings. Patient complexity varies over time and according to the place of treatment, requiring multiple actors, and usual guidelines are rarely applicable. As multiple organ systems are involved and the need for a "tailored" approach, these patients are often hospitalized in general internal medicine wards.
View Article and Find Full Text PDF