Screening for proline‑rich protein 11 gene expression in cervical cancer: Use as a novel diagnostic biomarker and poor prognostic factor.

Cervical cancer is the fourth most common type of cancer affecting the female population worldwide, and it is associated with a late diagnosis and a poor prognosis. It is thus imperative to improve modern diagnostic methods by searching for novel tumor biomarkers, such as proline-rich protein 11 (PRR11), the expression of which is deregulated in various types of cancer and participates in their cellular progression. However, the involvement of PRR11 in cervical cancer has not yet been fully elucidated.

Paget disease of de Vulva: About a rare case and a literature review.

Introduction: Paget disease of de Vulva (PDV) is a rare neoplastic intraepithelial pathology. In the majority of cases, neoplastic proliferation remains intraepithelial and the prognosis is favorable. The standard treatment for Paget disease is surgical excision.

Neuroendocrine carcinoma of the cervix: About a rare case and literature review.

Introduction: Neuroendocrine carcinomas of the uterine cervix are rare carcinomas, accounting for only 0.9-1.5 % of cervical tumors.

The value of surgery in the treatment of gestational choriocarcinoma: A case report.

Introduction And Importance: Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor.

Case Presentation: We report a rare case of gestational choriocarcinoma in a young woman initially classified as low risk (FIGO2), treated by surgery after chemoresistance to different chemotherapy protocols, marked by an excellent clinical and biochemical improvement.

Unilateral ovarian metastasis from renal clear cell carcinoma.

Introduction And Importance: Ovarian metastases of renal origin are rarely reported in the literature and pose a diagnostic problem because they are usually diagnosed at a distance from the primary cancer.

Presentation Of Case: We report a case of unilateral ovarian metastasis from clear cell renal cell carcinoma fifteen years after nephrectomy in a fifty-six-year-old patient who underwent surgery for an abdominopelvic mass.

Clinical Discussion: The diagnosis of ovarian metastases can be made at the same time as the diagnosis of the primary cancer or at a distance from it, with an interval ranging from a few months to years later.