Publications by authors named "M Benhamida"

Article Synopsis
  • A study examined the prevalence and incidence of interstitial lung disease in children (chILD) in France, finding it affects 44 children per million in 2022 and has an incidence of 4.4 per million.
  • The research included data from 790 patients across 42 centers, noting that the median age for diagnosis was 3 months, with a significant portion having familial forms.
  • Management typically involved oxygen therapy and corticosteroids, with survival rates being 57.3% for children diagnosed before 2 years and 86% for those diagnosed between 2 and 18 years; the study highlights the need for improved international data collection and standardized practices.
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Three-dimensional tumorsphere cultures recapitulate the expression of several cancer stem cell (CSC) biomarkers and represent an effective in vitro platform to screen the anti-CSC properties of drugs. Whereas ovarian carcinoma is among the leading causes of death for women, ovarian CSC (OvCSC), a highly malignant subpopulation of ovarian cancer cells, is thought to be responsible for therapy resistance, metastasis, and tumor relapse. Epigallocatechin-3-gallate (EGCG), a diet-derived active polyphenol found in green tea leaves, can suppress ovarian cancer cell proliferation and induce apoptosis.

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Article Synopsis
  • Automated molecular panels, like the Eazyplex CSF direct M panel, are being evaluated for their effectiveness in diagnosing meningitis from cerebrospinal fluid (CSF) samples.
  • The study analyzed 230 CSF samples over three years, with results showing a positive rate of 13.9%, and significant findings related to false positives and negatives due to prior antibiotic treatment.
  • Overall, the Eazyplex showed strong diagnostic performance, particularly useful when patients have received antibiotics before the lumbar puncture, with high accuracy rates in identifying true positive and negative samples.
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Cystic fibrosis (CF) arises from mutations in the CF transmembrane conductance regulator () gene, resulting in progressive and life-limiting respiratory disease. R751L is a rare CFTR mutation that is poorly characterized. Our aims were to describe the clinical and molecular phenotypes associated with R751L.

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