Publications by authors named "M Benassarou"

The vascularized periosteal free flap transposes a non-irradiated soft tissue with neoangiogenesis, bone induction, and osteogenesis qualities. A surgical technique using a humeral periosteal free flap is described for the treatment of recurrent osteoradionecrosis of the lower jaw. The humeral periosteal free flap is a technique associated with low morbidity.

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Article Synopsis
  • Primary chronic Non-Bacterial Osteomyelitis of the jaw is a rare inflammatory disease that shares similarities with SAPHO syndrome and chronic recurrent multifocal osteomyelitis, and TNF-alpha blockade may be an effective treatment option despite limited clinical data.
  • In a study of 15 patients with refractory CNOM, 10 were treated with anti-TNF-alpha therapy due to previous treatment failures and the promising efficacy seen in related conditions.
  • The results showed that most patients experienced rapid and lasting remission without serious side effects, though male patients appeared to have poorer outcomes, indicating that TNF-alpha blockade is both safe and effective for CNOM management.
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Raine syndrome (RNS) is a rare autosomal recessive osteosclerotic dysplasia. RNS is caused by loss-of-function disease-causative variants of the FAM20C gene that encodes a kinase that phosphorylates most of the secreted proteins found in the body fluids and extracellular matrix. The most common RNS clinical features are generalized osteosclerosis, facial dysmorphism, intracerebral calcifications and respiratory defects.

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Background And Objective: The prevalence of extensive skin cancers increases with the aging of the population. Surgical management is the gold standard of curative treatment while morbidity is not negligible. There are few data in the literature concerning extensive head and neck cutaneous cancers.

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Introduction: Approximately 80,000 cases of skin cancer are diagnosed annually in France. The management of these cancers can occur in both university hospital centers and ambulatory surgery centers. Limited data exist regarding the epidemiology of cutaneous cancers treated through ambulatory surgery centers.

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