Publications by authors named "M Belan"

Background: Nocardiosis, a bacterial opportunistic infection caused by spp, has recently been reported in patients with anti-granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibodies, but insufficient data are available about disease presentation, outcomes, and occurrence of autoimmune pulmonary alveolar proteinosis (aPAP) in this population.

Methods: We performed a prospective, multicenter, nationwide study in France and included patients with a infection who had anti-GM-CSF autoantibodies. We describe their clinical, microbiological, and radiological characteristics, and their outcome at 1 year of follow-up.

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  • A retrospective study conducted in a medical ICU from 2016 to 2020 examined cases of bloodstream infections (BSI) caused by Klebsiella pneumoniae, focusing on a hypervirulent strain (hvKP).
  • Out of 70 patients with K. pneumoniae BSI, 9 (13%) were identified with hvKP, with a significant number (56%) having pneumonia as the cause of the infection.
  • The study highlighted that a considerable portion of hvKP-BSI patients were homeless (56%), and while the 30-day mortality rate was high (44%), it did not significantly differ from that of classical Klebsiella pneumoniae BSI (cKP).
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  • The study examined the effectiveness and safety of ChatGPT-4 in managing patients with positive blood cultures in a hospital setting over four weeks.
  • ChatGPT-4 provided comprehensive management plans that matched the recommendations of infectious disease consultants in about 59% of cases, but had limitations in diagnostic accuracy and appropriate treatment options.
  • The research concluded that relying solely on ChatGPT-4 for medical advice can be risky, particularly for severe infections, highlighting the need for expert oversight.
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