Publications by authors named "M Bebin"
Article Synopsis
- The 2023 American Epilepsy Society Annual Course focused on the importance of timing in evaluating and treating epilepsy, especially for vulnerable populations and those facing health disparities.
- The course covered a wide range of topics, including gaps in epilepsy care, behavioral health optimization, seizure forecasting, and treatment timing for various seizure types and conditions.
- Key discussions included the role of neuromodulation versus surgery, strategies for autoimmune-associated epilepsy, dietary therapy, and leveraging new biomarkers in collaboration with neuropsychological outcomes.
Article Synopsis
- The study aims to describe the phenotypic and genotypic spectrum of a neurodevelopmental disorder linked to a specific gene implicated in periventricular nodular heterotopia (PVNH).
- Researchers examined 17 individuals with variants, identifying several types of genetic mutations and their effects on brain structure and function.
- Findings highlighted a range of symptoms, including intellectual disability, seizures, microcephaly, and various neurological and sensory defects, confirming the gene's role in this autosomal dominant syndrome characterized by abnormal neuronal migration.
Objective: Tuberous sclerosis complex (TSC) is highly associated with autism spectrum disorder (ASD). Objectives of the study were to characterize autistic features in young children with TSC.
Methods: Participants included 138 children followed from ages 3 to 36 months with TSC from the Tuberous Sclerosis Complex Autism Center of Excellence Research Network (TACERN), a multicenter, prospective observational study aimed at understanding the underlying mechanisms of ASD in TSC.
This is a summary report of clinical and regulatory issues discussed at the 2018 NINDS workshop, entitled "Accelerating Therapies for Antiepileptogenesis and Disease Modification." The intent of the workshop was to optimize and accelerate development of therapies for antiepileptogenesis (AEG) and disease modification in the epilepsies. The working group discussed nomenclature for antiepileptogenic therapies, subdividing them into "antiepileptogenic therapies" and "disease modifying therapies," both of which are urgently needed.
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