Publications by authors named "M Bebenek"
Article Synopsis
- The study aimed to identify predictive factors for clinical complete response (cCR) in patients undergoing a watch-and-wait strategy after preoperative radiotherapy.
- A total of 490 patients were analyzed; 73 achieved cCR, with varying rates based on cancer risk levels: 39.0% for low-risk, 16.8% for intermediate-risk, and only 5.4% for high-risk cancers.
- Significant predictors for achieving cCR included tumor volume and nodal status, raising concerns about the viability of the watch-and-wait approach for patients with larger or circular tumors.
Surgical interventions in patients with peritoneal metastases combined with hyperthermic intraperitoneal chemotherapy (HIPEC) and systemic treatment are becoming more common and, when applied to selected patient groups, they reach 5-year survival rates of 32-52%. Good clinical outcomes require experienced and well-equipped healthcare centers, experienced surgical team and adequate patient qualification process. As a result of the discussion on the need for evaluation of quality of care and treatment outcomes and at the request of the Peritoneal Cancer Section of the Polish Society of Surgical Oncology, accreditation standards have been developed and the Accreditation Committee has been established for healthcare centers providing cytoreductive surgery and HIPEC for the management of primary and secondary peritoneal cancers.
View Article and Find Full Text PDFIntroduction: Nursing staff is burdened by high workload and stress. Furthermore, heavy lifting, as well as transferring nursing home residents, cause lumbar tissue damage and back pain. Exercise intervention studies to reduce work-related problems are rare and the evidence for efficacy of studies among nurses is limited.
View Article and Find Full Text PDFTriple-negative breast cancer (TNBC) is characterized by limited survival, poor prognosis, and high recurrence. Understanding the metabolic adaptations of TNBC could help reveal improved treatment regiments. Here we performed a comprehensive H NMR metabolic characterization of the MDA-MB-468 cell line, a commonly used model of TNBC, followed by an analysis of serum samples obtained from TNBC patients and healthy controls.
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