Publications by authors named "M Beattie"

Article Synopsis
  • - The complex nature of spinal cord injury (SCI) creates challenges for translating research into practical treatments, leading to a need for advanced data science solutions to manage diverse injury data and outcomes.
  • - To address privacy concerns with sensitive data, a Private Data Commons for SCI (PDC-SCI) has been developed, enabling secure, organized data sharing among researchers for collaborative studies.
  • - An example of PDC-SCI in action is demonstrated through the VA Gordon Mansfield SCI Consortium, which integrates various data types to enhance research insights and knowledge discovery in SCI.
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Article Synopsis
  • - The study aimed to compare the motor examinations done by the clinical neurosurgery team with the ISNCSCI assessments, since the latter can be time-consuming and impractical during acute spinal cord injuries.
  • - Researchers analyzed data from the TRACK-SCI registry, which included 72 pairs of motor examinations from 63 patients, and found strong correlations between the two methods, indicating that neurosurgery motor examinations can effectively substitute for ISNCSCI exams.
  • - The results showed a very high agreement between the scores from both types of examinations with low bias, suggesting that clinical neurosurgery evaluations are reliable for assessing neurological function after spinal cord injuries.
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Article Synopsis
  • Clostridium difficile infection (CDI) poses a significant public health risk, with few prevention methods available.* -
  • Researchers developed a multivalent mRNA-lipid nanoparticle vaccine that stimulates strong immune responses in various animal models, unaffected by gut microbiota changes.* -
  • The vaccine effectively protects mice from severe CDI and enhances the elimination of harmful bacteria from the gut, highlighting mRNA-LNP technology as a potential new treatment avenue.*
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Dobutamine stress cardiac magnetic resonance (dsCMR) has demonstrated value in identifying patients at risk for adverse cardiovascular events in adults with coronary artery disease, but its prognostic value in younger patients is unknown. This study sought to evaluate the relationship between dsCMR results and the risk of subsequent cardiovascular events in children. Patients age < 23 years who underwent dsCMR at Boston Children's Hospital were eligible for inclusion.

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Introduction: Recruitment of care home staff to research studies is recognised as challenging. This was further exacerbated by the COVID-19 pandemic and the associated negative media portrayal of care home workers. Social media use has surged since the onset of COVID-19 lockdowns, offering a plausible approach to understanding the barriers to care home research recruitment and gaining insight into public perceptions of care home workers.

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