Comparing traditional surveys and web-scraped data to understand the pigeon racing industry in Southern California.

Recent outbreaks of virulent Newcastle disease (vND) in domestic poultry in Southern California have raised questions as to the source(s) and the mode(s) of transmission. While pigeons have been found to be capable of transmitting a variant of Newcastle disease virus (NDV) known as Pigeon paramyxovirus-1 (PPMV-1) to other avian species including poultry, the potential geographic distribution and scope of transmission from racing pigeons to other domestic poultry in Southern California is poorly understood. In order to better understand the potential risk of transmission of vND from racing pigeons to domestic poultry, an extension-initiated survey was conducted in addition to social-media based analysis of racing pigeon activity associated with postings on a web-based popular classified advertisement (CAW) in Southern California.

Molecular detection of gene from methicillin-resistant isolated from clinical and environmental samples and its potential inhibition by phytochemicals using in vitro and in silico approach.

The increasing prevalence of Methicillin-resistant (MRSA) has posed significant challenges in clinical and environmental settings. MRSA's resistance is attributed to the gene, which encodes the penicillin-binding protein 2a (PBP2a), conferring resistance to β-lactam antibiotics. This study aimed to molecularly detect the gene in MRSA isolates from clinical and environmental samples and identify potential inhibitors of PBP2a using in vitro and in silico approaches.

Geospatial Distribution, Accessibility and Utilization of Basic Emergency Obstetric and New-born Care in Jigawa State, Northwest Nigeria.

Background: High maternal mortality has remained a problem, especially in developing countries. Ensuring availability and utilization of Basic Emergency Obstetric and Newborn Care services (BEmONC) reduce maternal morbidity and mortality. The study aimed to determine the geospatial distribution, accessibility and utilization of BEmONC services in Jigawa State.

Synthesis, molecular dynamics simulation and antimicrobial activity of novel s-triazine clubbed with three different hybrid pharmacophores.

To address microbial infections and combat drug resistance, we designed, synthesized, and evaluated three novel s-triazine clubbed pharmacophores: 1-acetylpyrazoline (5a-e), 2-aminopyrimidine (6a-e), and 1,5-benzodiazepine (7a-e). These were derived from chalcone (4a-e), showing improved pharmacological profiles. The compounds underwent characterization by FTIR, NMR, and Mass Spectroscopy, and their antimicrobial activities, along with structure-activity relationships (SAR), were assessed using in silico and in vitro methods.