Publications by authors named "M Baronio"
Venous leg ulcers are one of the most common nonhealing conditions and represent an important clinical problem. The application of pulsed radiofrequency electromagnetic fields (PRF-EMFs), already applied for pain, inflammation, and new tissue formation, can represent a promising approach for venous leg ulcer amelioration. This study aims to evaluate the effect of PRF-EMF exposure on the inflammatory, antioxidant, cell proliferation, and wound healing characteristics of human primary dermal fibroblasts collected from venous leg ulcer patients.
View Article and Find Full Text PDFArticle Synopsis
- The STAT1 gain-of-function syndrome leads to chronic mucocutaneous candidiasis and can also cause various other infections, autoimmune issues, and malignancies due to severe lymphopenia.
- In a study of seven patients with this condition, it was found that increased T lymphocyte apoptosis occurs, especially when stimulated, and treatment with the JAK inhibitor ruxolitinib showed promise in reducing this apoptosis and improving lymphopenia.
- The findings suggest that JAKinib therapy could be beneficial for treating not only chronic candidiasis and lymphopenia but also for managing increased interferon responses in patients with autoimmune or autoinflammatory symptoms.
Sensorineural Hearing Loss Is an Unrecognized Complication of Common Variable Immunodeficiency.
J Investig Allergol Clin Immunol
June 2024
Monogenic forms of common variable immunodeficiency and implications on target therapeutic approaches.
Curr Opin Allergy Clin Immunol
December 2023
Purpose Of Review: Common variable immunodeficiency (CVID) is the most common symptomatic inborn error of immunity. The disorder is characterized by variable clinical and immunological manifestations, and, in a small minority of patients, a monogenic cause may be identified. In this review, we focalized on three different monogenic forms of CVID-like disease.
View Article and Find Full Text PDF