Publications by authors named "M Barbaresi"

Background: The human sensorimotor system can naturally synchronize with environmental rhythms, such as light pulses or sound beats. Several studies showed that different styles and tempos of music, or other rhythmic stimuli, have an impact on physiological rhythms, including electrocortical brain activity, heart rate, and motor coordination. Such synchronization, also known as the "entrainment effect", has been identified as a crucial mechanism impacting cognitive, motor, and affective functioning.

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  • - The study investigates the distribution of the synthetic cathinone MDPHP in post-mortem specimens of a 30-year-old man, highlighting high concentrations in urine and gastric content, suggesting potentially lethal levels.
  • - Various toxicological analyses, including gas chromatography and liquid chromatography, were used to measure MDPHP and other substances, with no evidence of recent cocaine injection found.
  • - Findings indicated that MDPHP levels were significantly higher compared to previously reported fatal cases, leading the researchers to conclude that the individual's death was likely due to MDPHP overdose.
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  • * A study involving students from three universities evaluated their alcohol consumption through questionnaires and a scientific method (hEtG analysis), finding that 77.1% of samples either tested negative for alcohol metabolites or showed very low levels, suggesting minimal chronic excessive drinking.
  • * The research revealed low self-reported abstinence from alcohol (only 2.8%) compared to higher rates for tobacco (65.3%) and coffee (16.7%), indicating a potential opportunity for public health initiatives to promote responsible drinking habits among students.
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Scientific Background: Environmental sampling of SARS-CoV-2 is a fundamental tool for evaluating the effectiveness of non-specific prophylaxis measures in counteracting virus spread. The purpose of our work was to evaluate the effectiveness of the different sampling methods in the hospital setting to assess their correlation with the structural, functional, and operational situation of the monitored departments and to define the dynamics of the spread of the virus in indoor environments.

Methods: The monitoring (air bubbling sampling, surface wipe test) was carried out at the San Martino Polyclinic Hospital (Genoa, Italy) in the period since April 2020 to June 2021.

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  • - This study explores how the circadian clock impacts nutrient absorption and metabolism, particularly focusing on the differences between shift workers and daytime workers.
  • - Researchers measured gene expression in blood samples from 15 healthy volunteers at different times throughout the day, finding that gene expression peaked in the morning and was higher in shift workers compared to daytime workers.
  • - The findings suggest a link between higher gene expression levels and obesity-related factors such as body mass index, indicating that monitoring these levels could help address metabolic disorders related to circadian rhythm disruptions in shift workers.
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