DICE: fast and accurate distance-based reconstruction of single-cell copy number phylogenies.

Somatic copy number alterations (sCNAs) are valuable phylogenetic markers for inferring evolutionary relationships among tumor cell subpopulations. Advances in single-cell DNA sequencing technologies are making it possible to obtain such sCNAs datasets at ever-larger scales. However, existing methods for reconstructing phylogenies from sCNAs are often too slow for large datasets.

Management and Outcomes of Pulmonary Embolism in Women of Reproductive Age Admitted to Urban Versus Rural Areas Compared to Men.

There are limited and conflicting data on sex and urban-rural disparities in outcomes of patients with pulmonary embolism (PE) in the reproductive age group. Our object was to assess sex disparities in the reproductive age group cohort. All adult non-elective admissions in the reproductive age group (18-49 years) with a primary diagnosis of PE and with no missing sex/age data were identified using the National Inpatient Sample.

Synergy of adsorption and visible light-induced photocatalytic degradation of doxycycline by cellulose modified CuAl layered double hydroxide binary composite.

The problem of antibiotic-induced water pollution has attracted public attention in the modern world. Antibiotics have the capacity to cause massive hazardous damage at very low dosages due to their long-lasting biological stability. To address this issue, a new highly stable, reusable, greener, nontoxic, easily accessible composite material (CuAl-LDH/CL) consisting of Cellulose (CL) modified CuAl-layered double hydroxide was successfully synthesized.

Attainment of low-density lipoprotein cholesterol goals in patients undergoing coronary revascularization in the contemporary clinical practice.

This study aimed to assess the effectiveness of current lipid-lowering therapy in achieving low-density lipoprotein cholesterol (LDL-C) goals in Indian patients undergoing coronary revascularization. Consecutive subjects (n = 1275, mean age 60.0 ± 9.

Left ventricular myocardial deformation in patients on maintenance haemodialysis.

Background: Patients with chronic kidney disease (CKD) undergoing maintenance haemodialysis (MHD) develop several abnormalities of left ventricular (LV) structure and function. Speckle-tracking echocardiography permits compressive assessment of LV myocardial deformation. Previous studies involving CKD patients have shown a significant reduction in LV global longitudinal strain (GLS) with strong prognostic implications.