Hashimoto's Encephalopathy with Use of Intravenous Immunoglobulin as First-Line Therapy.

Hashimoto's encephalopathy is an uncommon cause of altered mental status in hospitalized patients and is challenging to diagnose, particularly in the presence of other psychiatric comorbidities. Corticosteroids are the primary treatment. Here, we present a patient with history of post-traumatic stress disorder and prior substance abuse admitted with profound altered mental status and agitation requiring admission to the intensive care unit and mechanical ventilation.

Griseofulvin Radiosensitizes Non-Small Cell Lung Cancer Cells and Activates cGAS.

Extra copies of centrosomes are frequently observed in cancer cells. To survive and proliferate, cancer cells have developed strategies to cluster extra-centrosomes to form bipolar mitotic spindles. The aim of this study was to investigate whether centrosome clustering (CC) inhibition (CCi) would preferentially radiosensitize non-small cell lung cancer (NSCLC).

Systems thinking as a pathway to global warming beliefs and attitudes through an ecological worldview.

Prior research has found that systems thinking, the tendency to perceive phenomena as interconnected and dynamic, is associated with a general proenvironmental orientation. However, less is known about its relationship with public understanding of climate change and/or whether this relationship varies across people with different political views. Because climate change is a highly politicized issue, it is also important to understand the extent to which systems thinking can foster acceptance of climate science across political lines.

Diverse segments of the US public underestimate the environmental concerns of minority and low-income Americans.

In a nationally representative survey experiment, diverse segments of the US public underestimated the environmental concerns of nonwhite and low-income Americans and misperceived them as lower than those of white and more affluent Americans. Moreover, both whites and nonwhites and higher- and lower-income respondents associated the term "environmentalist" with whites and the well-educated, suggesting that shared cultural stereotypes may drive these misperceptions. This environmental belief paradox-a tendency to misperceive groups that are among the most environmentally concerned and most vulnerable to a wide range of environmental impacts as least concerned about the environment-was largely invariant across demographic groups and also extended to the specific issue of climate change.