The effectiveness of acceptance and commitment therapy in reducing the symptoms of complicated grief, corona disease anxiety, and improving the quality of life in the survivors of the deceased due to COVID-19.

Background: COVID-19 is an infectious disease that has threatened the physical and mental health of people and in many cases leads to death. The present study investigated the effectiveness of acceptance and commitment therapy (ACT) in reducing the symptoms of complicated grief, and corona disease anxiety, and improving the quality of life in the survivors of the deceased due to COVID-19.

Materials And Methods: The research method was an experimental design with pre-test, post-test, and follow-up with a control group and random assignment to the intervention and the control groups.

Effect of selective and family-based prevention on addiction susceptibility, affiliation with deviant peers, risk-taking, and risk and protective factors of substance use in high-risk adolescents: A randomized clinical trial.

Background: Adolescents with a background in families affected by substance use exhibit an increased susceptibility to developing individual substance-related or other mental disorders. Consequently, they represent a crucial demographic for targeted preventive interventions. The current study examined the impact of selective prevention (SP) and family-based prevention (F-BP) measures on addiction susceptibility, affiliation with deviant peers (ADP), risk-taking, and risk and protective factors (RPFs) related to substance use among high-risk adolescents.

The impact of epithelial-mesenchymal transition (EMT) induced by metabolic processes and intracellular signaling pathways on chemo-resistance, metastasis, and recurrence in solid tumors.

The intricate cellular process, known as the epithelial-mesenchymal transition (EMT), significantly influences solid tumors development. Changes in cell shape, metabolism, and gene expression linked to EMT facilitate tumor cell invasion, metastasis, drug resistance, and recurrence. So, a better understanding of the intricate processes underlying EMT and its role in tumor growth may lead to the development of novel therapeutic approaches for the treatment of solid tumors.

The association between age of menopause and type 2 diabetes: a systematic review and meta-analysis.

Background: Type-2 diabetes mellitus (T2DM) is considered one of the chronic diseases that can have a relationship with age of menopause onset. Several studies have revealed that early menopause or late menopause can have a correlation with type-2 diabetes. This systematic review and meta-analysis aimed to investigate the association between the age of menopause onset and type-2 diabetes.