Publications by authors named "M Baiardo Redaelli"

Background: Acute kidney injury (AKI) is a frequent and important complication of cardiac surgery. Decreased perfusion is a key mechanism. This decreased perfusion may be attenuated by intravenous amino acids (AAs) through recruitment of renal functional reserve.

View Article and Find Full Text PDF

Female BRCA1/2 pathogenic variant (PV) carriers face substantial risks for breast and ovarian cancer. Evidence-based decision aids (DAs) can facilitate these women in their decision-making process on an individually suitable preventive strategy. However, there is a gap in previous literature exploring whether DA effectiveness varies according to women's age.

View Article and Find Full Text PDF
Article Synopsis
  • Acute kidney injury (AKI) is a frequent complication that can occur during surgery, and currently, there's no proven single method for its prevention; intravenous amino acids (AA) might help protect kidney function during this period.
  • A meta-analysis of 15 studies (involving over 4,500 patients) showed that patients receiving AA had a lower incidence of AKI (24.7%) compared to those who didn't (30.1%), indicating a significant potential benefit of AA infusion.
  • The findings also revealed that AA administration not only lowered the risk of AKI but also reduced serum creatinine levels and hospital stays while improving kidney function.
View Article and Find Full Text PDF

Background: Women with pathogenic variants (PV) of the genes BRCA1/2 have a choice of preventive options. To help these women decide for themselves, we developed and implemented a decision coaching (DC) program and evaluated it for congruence between the participants' desired and actual roles in decision-making.

Methods: Healthy BRCA1/2 PV carriers (25-60 years of age) were recruited at six centers in Germany.

View Article and Find Full Text PDF

Objective: To identify factors contributing to baseline knowledge in women with BRCA1/2 pathogenic variants (PVs) and knowledge gain after decision aid (DA) use.

Methods: Women with PVs in BRCA1 or BRCA2 genes were randomly assigned to an intervention group (IG) receiving DAs or a control group (CG). Of the total sample, 417 completed the baseline survey and were included in this analysis.

View Article and Find Full Text PDF