Publications by authors named "M Bahaddin Acat"
Background: Despite Non-small cell lung cancer (NSCLC) ranks among the most deadly cancers worldwide, and currently, apart from a low percentage, targetable molecules have not been identified in its etiopathogenesis. The relationship between the proteoglycans decorin and biglycan, which are present in the extracellular matrix of cells, and transforming growth factor Beta-1 (TGF-B1), has been shown in many cancers. We investigated the significance of these molecules in NSCLC.
View Article and Find Full Text PDFAim: The current study aimed to evaluate the effects of caspase-8 (CASP8) and mitogen-activated protein kinase 1 (MAPK1) gene expression levels and their products on preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Methods: A total of 40 patients (men, 15 [37.5%]; women, 25 [62.
Aim: We aimed to investigate the effect of short-term pirfenidone treatment on prolonged COVID-19 pneumonia.
Method: Hospital files of patients hospitalised with a diagnosis of critical COVID-19 pneumonia from November 2020 to March 2021 were retrospectively reviewed. Chest computed tomography images taken both before treatment and 2 months after treatment, demographic characteristics and laboratory parameters of patients receiving pirfenidone + methylprednisolone (n = 13) and only methylprednisolones (n = 9) were recorded.
Aim: Obstructive sleep apnea syndrome (OSAS) is a chronic and incapacitating disease that often requires lifelong care. This study aimed to evaluate the thiol/disulfide homeostasis in patients with OSAS, to compare the thiol/disulfide levels with the control group and to investigate their relationship with the severity of the disease.
Material And Methods: Patients who were admitted to the department of chest diseases, and diagnosed with OSAS using polysomnographic analysis ( = 186) and 144 patients who underwent polysomnography due to some reasons but ruled out of having OSAS were included in the study.
Article Synopsis
- - This study examined the relationship between cancer symptoms and insomnia in lung cancer patients in Turkey, highlighting the high prevalence of sleep-related issues among these individuals.
- - Among 1245 lung cancer patients, significant percentages reported insomnia (44.7%), daytime sleepiness (60.8%), and fatigue (82.1%), with certain demographics, such as gender and disease stage, linked to higher insomnia rates.
- - The findings indicate that effective management of cancer symptoms is crucial for improving sleep quality in lung cancer patients, as those with more severe symptoms experienced greater sleep disturbances.