Publications by authors named "M Badrignans"

Background: Mycosis fungoides (MF) usually has an indolent course. However, some patients develop more aggressive disease and few prognostic parameters have been identified. Isolated cases of pustular MF (pMF) suggest an unfavourable prognosis.

View Article and Find Full Text PDF

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare but well-defined entity, often associated with autoimmune manifestations, generally with a good prognosis unless associated with hemophagocytic syndrome. Typically, the lymphoma cells rim the adipocytes and are characterized by a CD8 + cytotoxic phenotype. We report 2 cases of SPTCL where the first biopsies only showed subcutaneous fat necrosis without any lymphoma cell visible.

View Article and Find Full Text PDF
Article Synopsis
  • - This study analyzed severe blistering skin reactions caused by immune checkpoint inhibitors (ICI) in 32 patients, emphasizing that such reactions, although rare, can be life-threatening and are often misdiagnosed as epidermal necrolysis (EN).
  • - The research found that symptoms like fever, ocular involvement, and extensive skin detachment were more common in patients diagnosed with EN compared to those with lichenoid dermatosis (LD) or unclassified dermatosis (UD), highlighting the need for careful diagnostic review.
  • - Treatment usually involved corticosteroids, and 25% of patients died during the acute phase; however, most did not restart the ICI, suggesting a potential issue with management approaches that need further consensus and clarity
View Article and Find Full Text PDF