Publications by authors named "M Backorova"
Article Synopsis
- - The study used a scanning electron microscope with energy dispersive X-ray analysis to examine the elemental composition of the leaves of two plant species, Vaccinium myrtillus and Vaccinium vitis-idaea, from both clean and polluted areas.
- - Results showed that the mine-polluted soil had higher levels of 11 elements, leading to significant changes in the leaves, particularly increased contents of certain elements in V. myrtillus, while V. vitis-idaea experienced decreased levels in most elements.
- - The environmental impact also affected the production of phytochemicals, with V. myrtillus showing increased flavonoid levels while V. vitis-idaea saw a significant decrease, highlighting the importance of knowing
Candida albicans, a polymorphic yeast, is a physiological component of the human and animal commensal microbiome. It is an etiological factor of candidiasis, which is treated by azole antifungals. Growing resistance to azoles is a reason to look for other alternative treatment options.
View Article and Find Full Text PDFNatural products include a diverse set of compounds of drug discovery that are currently being actively used to target tumor angiogenesis. In the present study, we evaluated the anti-angiogenic activities of secondary metabolite usnic acid isolated from We investigated the in vitro effects on proliferation, migration, and tube formation of VEGF- and bFGF-stimulated HUVECs. Ex ovo anti-angiogenic activity was evaluated using the CAM assay.
View Article and Find Full Text PDFLichens comprise a number of unique secondary metabolites with remarkable biological activities and have become an interesting research topic for cancer therapy. However, only a few of these metabolites have been assessed for their effectiveness against various in vitro models. Therefore, the aim of the present study was to assess the effect of extract (L.
View Article and Find Full Text PDFZinc oxide nanoparticles phytotoxicity on halophyte from genus Salicornia.
Plant Physiol Biochem
September 2018
Article Synopsis
- This study examines how zinc oxide nanoparticles (ZnO NPs) affect the growth of Salicornia, a type of halophyte, showing that higher concentrations (1000 mg/L) can reduce shoot length by over 50% compared to untreated plants.
- The negative impact on plant growth is linked to the release of free zinc(II) ions and the generation of reactive oxygen species (ROS), which alter antioxidant enzyme activities and cause lipid peroxidation.
- Ultimately, excessive ROS and zinc imbalances trigger oxidative stress, leading to programmed cell death, indicating that even stress-resistant halophytes can suffer from ZnO NPs exposure.