Publications by authors named "M B Winkel"

Article Synopsis
  • International guidelines for imaging follow-up after pancreatic resection for pancreatic ductal adenocarcinoma (PDAC) are inconsistent, leading to varied follow-up strategies globally.
  • The study aimed to compare clinical outcomes, including treatment for recurrence and survival rates, between patients who received either symptomatic follow-up or routine imaging after PDAC surgery across 33 international centers.
  • A total of 333 patients were analyzed, showing that 29% had symptomatic follow-up while 71% underwent routine imaging, with overall survival rates being examined through statistical methods to identify the impact of the follow-up strategy on patient outcomes.
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In recent decades, field and semi-field studies of malaria transmission have gathered geographic-specific information about mosquito ecology, behaviour and their sensitivity to interventions. Mathematical models of malaria transmission can incorporate such data to infer the likely impact of vector control interventions and hence guide malaria control strategies in various geographies. To facilitate this process and make model predictions of intervention impact available for different geographical regions, we developed AnophelesModel.

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Objectives: This article defines analytical performance specifications (APS) for evaluating laboratory proficiency through an external quality assessment scheme.

Methods: Standard deviations for proficiency assessment were derived from Thompson's characteristic function applied to robust data calculated from participants' submissions in the Occupational and Environmental Laboratory Medicine (OELM) external quality assurance scheme for trace elements in serum, whole blood and urine. Characteristic function was based on two parameters: (1) β - the average coefficient of variation (CV) at high sample concentrations; (2) α - the average standard deviation (SD) at low sample concentrations.

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