Does Leak Matter? A Novel Dynamic Leak Model to Simulate Leak for Performance Testing of Manual Neonatal Resuscitation Devices. A Bench Study.

Introduction: Newborn resuscitation is commonly performed in the presence of face mask leak. Leak is highly variable, pressure-dependent and often unrecognized. The effectiveness of resuscitation devices to deliver adequate inflations in the presence of leak is unknown.

Electrocatalytic Nitrite Reduction by a Monomeric NrfA: Commonality in Ammonification Mechanisms.

Cytochrome nitrite reductase (NrfA) is a pentaheme enzyme capable of the six-electron reduction of nitrite to ammonia, which is a key step in the nitrogen cycle. All NrfA enzymes appear to have a branched set of two heme-based pathways for electron transfer to a conserved active site, and until recently, NrfA enzymes from a variety of microorganisms were considered to possess a homodimeric structure; yet, recent efforts have shown that in solution, purified () NrfA is a monomer. Direct protein electrochemistry has been used in the past to characterize the dimeric NrfAs from and , revealing features of maximal activity as a function of nitrite concentration, and redox poise, both of which were interpreted in terms of the dimeric structure providing multiple redox equivalents.

Physiological and transcriptional reprogramming for salinity tolerance of endangered mangrove associate Hernandia nymphaeifolia.

Background: Hernandia nymphaeifolia is a typical mangrove associate with high ecological, ornamental, and medicinal values, but in China, it has become endangered in recent years, and an urgent protection is needed. Salinity is a key factor for growth and survival of mangrove seedlings, and thus a comprehensive understanding of salt tolerance in mangroves is important for their conservation and afforestation. However, little is known regarding salt-responsive mechanisms in H.

Exploring Internurse Variation in Documentation of the Clinically Aligned Pain Assessment (CAPA) Tool.

Purpose: The Clinically Aligned Pain Assessment (CAPA) tool was developed to facilitate dialogue between clinicians and patients regarding pain, providing more comprehensive information than intensity ratings. However, inconsistency in its administration and documentation may limit its utility. The purpose of this study was to describe variation in nurses' CAPA documentation.

International QEEG Certification Board Guideline Minimum Technical Requirements for Performing Clinical Quantitative Electroencephalography.

Quantitative electroencephalogram (QEEG) is a technology which has grown exponentially since the foundational publication by in Science in 1997, introducing the use of age-regressed metrics to quantify characteristics of the EEG signal, enhancing the clinical utility of EEG in neuropsychiatry. Essential to the validity and reliability of QEEG metrics is standardization of multi-channel EEG data acquisition which follows the standards set forth by the American Clinical Neurophysiology Society including accurate management of artifact and facilitation of proper visual inspection of EEG paroxysmal events both of which are expanded in this guideline. Additional requirements on the selection of EEG, quality reporting, and submission of the EEG to spectral, statistical, and topographic analysis are proposed.