Publications by authors named "M B Thoefner"

Article Synopsis
  • Central neuropathic pain is a significant symptom of syringomyelia in both humans and Cavalier King Charles Spaniel dogs, prompting a study on the spinal cords of affected CKCS dogs.* -
  • The research aimed to examine if specific spinal structures involved in pain perception were damaged and whether this damage correlated with pain-related behaviors like phantom scratching.* -
  • Findings revealed volume loss in specific spinal cord regions in dogs exhibiting unilateral scratching, but no significant changes in cell density were observed, indicating the studied dogs were in advanced stages of syringomyelia.*
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Unwanted behaviour in mares is a commonly presenting problem to the veterinarian. This behaviour may range from the mare being uncooperative or aggressive when handled on the ground, kicking, bucking or rearing when ridden or being aggressive towards other horses. This purpose of the study was to evaluate whether bilateral ovariectomy in mares with unwanted behaviour improved the mare's behaviour and/or rideability from the owner's perspective.

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Sarcoids are common equine skin tumors where the risk of recurrence after treatment is high, and better treatment options are warranted. Calcium electroporation is a novel anti-cancer treatment where lethally high calcium concentrations are introduced into the cells by electroporation, a method where short high-voltage pulses induce transient permeabilization of the cell membrane. This study investigated the safety and long-term response of calcium electroporation on sarcoids.

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Objective: We aimed to assess the efficacy and benefit-risk profile of pregabalin (PGN) to reduce the clinical signs of central neuropathic pain (CNeP) as reflected by scratching episodes in dogs with symptomatic syringomyelia (SM).

Study Design: Randomized, double-blind, placebo-controlled crossover study.

Animals: A total of 12 client-owned Cavalier King Charles Spaniels (age, 1.

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It is assumed that Cavalier King Charles spaniels with Chiari-like malformation and syringomyelia experience central neuropathic pain. An association between spinal cord parenchymal lesions and specific clinical signs (e.g.

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