Vanillin and IGF1-loaded dual-layer multifunctional wound dressing with micro-nanofibrous structure for full-thickness wound healing acceleration.

Multifunctional dual-layer wound dressings hold significant promise for comprehensive full-thickness wound management by closely mimicking the native skin structure and features. Herein, we employed an innovative approach utilizing electrospinning techniques to develop a dual-layer dressing comprising a microfibrous Ecoflex®-Vanillin (Ex-Vnil) top layer (TL) and a nanofibrous Soluplus®-Insulin-like growth factor-1 (Sol-IGF1) bottom layer (BL). The tensile properties of dual-layer wound dressings were within the standard range for use in skin tissue regeneration.

Physicochemically Cross-linked Injectable Hydrogel: an Adhesive Skin Substitute for Burned Wound Therapy.

Burns carry a large surface area, varying in shapes and depths, and an elevated risk of infection. Regardless of the underlying etiology, burns pose significant medical challenges and a high mortality rate. Given the limitations of current therapies, tissue-engineering-based treatments for burns are inevitable.

Super-resolution expansion microscopy in plant roots.

Super-resolution methods provide far better spatial resolution than the optical diffraction limit of about half the wavelength of light (∼200-300 nm). Nevertheless, they have yet to attain widespread use in plants, largely due to plants' challenging optical properties. Expansion microscopy improves effective resolution by isotropically increasing the physical distances between sample structures while preserving relative spatial arrangements and clearing the sample.

The Effect of Mixed Articulation Therapy on Perceptual and Acoustic Features of Compensatory Errors in Children with Cleft Palate.

Background: Compensatory errors are a conventional part of an articulation disorder identified by speech pathologists in patients with Cleft palate (CP). This study aimed to evaluate the effect of new mixed articulation therapy on the perceptual and acoustic features of these errors.

Methods: The single-case experimental design, ABA design, was used in this study.

The Impact of Deep Local Lung Hyperthermia on COVID-19 Cancer Patients.

Background: The goal of this study was to assess the impact of deep local hyperthermia on oxygen (O) saturation and infected volumes of lungs on coronavirus disease 2019 (COVID-19) cancer patients.

Materials And Methods: Fifty patients who suffered from COVID-19 (according to their computed tomography (CT) images and laboratory findings) were included in this study. The mentioned patients were divided into two groups (I and II) with thirty-five participants.