Publications by authors named "M B Tanios"

Article Synopsis
  • The study investigates how often to screen critically ill adults on ventilators and the best method for conducting spontaneous breathing trials (SBT) to successfully extubate them.
  • It involves a randomized clinical trial with 797 participants who required mechanical ventilation, comparing once-daily and more frequent screenings alongside two SBT techniques: pressure-supported and T-piece.
  • Results show no significant differences in the time to successful extubation based on screening frequency or SBT technique, indicating that both methods may be similarly effective.
View Article and Find Full Text PDF
Article Synopsis
  • There may be a connection between driving pressure (∆P) during invasive mechanical ventilation (IMV) and patient outcomes, particularly in those with acute respiratory distress syndrome (ARDS) related to COVID-19 (C-ARDS).
  • This study aimed to see if maintaining a daily ∆P of less than 15 cm HO, in conjunction with low tidal volume ventilation (LTVV), improves 28-day mortality compared to using LTVV alone.
  • Results showed that while 28-day survival rates varied among the groups, limiting ∆P did not appear to provide significant additional survival benefits compared to LTVV alone, suggesting a need for further research in this area.
View Article and Find Full Text PDF

Spontaneous intraoperative development of Mobitz II second-degree atrioventricular block is a rare event which requires decisive action on the part of anesthesiologists and anesthetists. Given that this arrhythmia can be fatal if not properly managed, it is imperative that every practitioner know how it should be managed. Currently, there is a lack of literature discussing what to expect when a patient develops this complication and what the best management strategies are.

View Article and Find Full Text PDF
Article Synopsis
  • The FAST-NAWC trial is a multicenter study that aims to compare different screening frequencies and techniques for spontaneous breathing trials in critically ill patients on ventilation in 20 North American ICUs.
  • The original protocols have been updated to include COVID-19 patients, and changes were made to the statistical analysis plan to accommodate data reporting for both COVID-19 and non-COVID-19 participants.
  • The trial has been registered on Clinical Trials.gov, and this update outlines the key protocol modifications and their purpose before the final follow-up and data analysis phases.
View Article and Find Full Text PDF