Publications by authors named "M B Shine"
Article Synopsis
- The Dokkyo study aimed to evaluate the C-reactive protein-to-albumin ratio (CAR) as a predictor for S-1 chemotherapy tolerance in pancreatic cancer patients following surgery, building on findings from the Ehime study.
- In a cohort of 172 patients, those who completed S-1 treatment had a significantly lower CAR compared to non-completers, with a CAR cutoff value of 0.05 indicating a higher completion rate.
- The study confirmed that a higher postoperative CAR is a reliable risk marker for adverse events leading to S-1 non-completion after curative surgery for pancreatic cancer patients.
Background: Although clozapine is the most effective antipsychotic for people with treatment-resistant schizophrenia (TRS), only 40% of people with TRS respond, and there is limited evidence for augmentation agents. Cannabidiol (CBD) reduces positive symptoms in individuals with schizophrenia, but no trials have specifically examined its efficacy in those with clozapine-resistant schizophrenia.
Aims: To examine the clinical efficacy of CBD augmentation in people with clozapine-resistant schizophrenia.
Shorter Drainage Tube to the Pancreatic Stump Reduces Pancreatic Fistula After Distal Pancreatectomy.
Surg Laparosc Endosc Percutan Tech
December 2024
Background: We investigated the relationship between the length of a prophylactic closed-suction drainage tube and clinically relevant postoperative pancreatic fistula (CR-POPF) in distal pancreatectomy (DP).
Materials And Methods: The clinical data of 76 patients who underwent DP using a reinforced stapler for the division of the pancreas at Ehime University Hospital between December 2017 and May 2023 were retrospectively analyzed. Laparoscopic DP was performed in 41 patients (53.
Article Synopsis
- - This study looked at how the shape of the reconstructed portal vein/superior mesenteric vein (PV/SMV) affects long-term nutrition after pancreatic surgery (pancreatoduodenectomy) using a technique called computational fluid dynamics (CFD).
- - Twenty-four patients who had the surgery and were tumor-free for over 9 months were analyzed by creating 3D models from their CT scans taken 3-6 months post-surgery.
- - Results showed that patients with higher pressure or turbulence in blood flow were more likely to experience poorer nutritional recovery within 9 months, demonstrating that CFD can help assess the effectiveness of vein reconstructions.
Article Synopsis
- The study examined factors affecting the difficulty of laparoscopic liver resection (LLR), specifically the distance between the tumor and blood vessels.
- Out of 118 patients studied, 10 (8.5%) required conversion to open surgery, with findings showing that lower platelet counts and closer tumor-vessel proximity (within 10 mm) were significant risk factors.
- The results identified 10 mm as a critical cutoff distance for predicting conversion, making it an important consideration for improving surgical outcomes in LLR.