Individual return patterns of spawning flannelmouth sucker (Catostomus latipinnis) to a desert river tributary.

Tributaries provide temporal and spatial habitat heterogeneity in river networks that can be critical for parts of the life history of a species. Tributary fidelity can benefit individual fish undergoing spawning migrations by reducing time and energy spent exploring new areas and leveraging previous experience, but anthropogenic activities that fragment or degrade these systems can eliminate those benefits. We used multistate models based on passive integrated transponder (PIT) detection data from 2013 to 2023 to estimate the proportion of flannelmouth suckers (Catostomus latipinnis) migrating to a tributary, McElmo Creek, from the mainstem San Juan River for spawning.

Migration timing and tributary use of spawning flannelmouth sucker (Catostomus latipinnis).

Spawning phenology and associated migrations of fishes are often regulated by factors such as temperature and stream discharge, but flow regulation of mainstem rivers coupled with climate change might disrupt these cues and affect fitness. Flannelmouth sucker (Catostomus latipinnis) persisting in heavily modified river networks are known to spawn in tributaries that might provide better spawning habitat than neighboring mainstem rivers subject to habitat degradation (e.g.

Splicing factor deficits render hematopoietic stem and progenitor cells sensitive to STAT3 inhibition.

Hematopoietic stem and progenitor cells (HSPCs) sustain lifelong hematopoiesis. Mutations of pre-mRNA splicing machinery, especially splicing factor 3b, subunit 1 (SF3B1), are early lesions found in malignancies arising from HSPC dysfunction. However, why splicing factor deficits contribute to HSPC defects remains incompletely understood.

Exploring metapopulation-scale suppression alternatives for a global invader in a river network experiencing climate change.

Invasive species can dramatically alter ecosystems, but eradication is difficult, and suppression is expensive once they are established. Uncertainties in the potential for expansion and impacts by an invader can lead to delayed and inadequate suppression, allowing for establishment. Metapopulation viability models can aid in planning strategies to improve responses to invaders and lessen invasive species' impacts, which may be particularly important under climate change.

Intrahepatic microbes govern liver immunity by programming NKT cells.

The gut microbiome shapes local and systemic immunity. The liver is presumed to be a protected sterile site. As such, a hepatic microbiome has not been examined.