Publications by authors named "M B MYLES"
Background Aims: Despite promising results in pre-clinical studies, mesenchymal stromal cells (MSCs) face significant challenges in clinical translation. A scoping review by our group highlighted two key issues contributing to this gap: (i) lack of a clear and consensus definition for MSCs and (ii) under-reporting of critical parameters in MSC clinical studies. To address these issues, we conducted a modified Delphi study to establish and implement a consensus definition for MSCs and develop reporting guidelines for MSC clinical studies.
View Article and Find Full Text PDFImportance: Technical skill in complex surgical procedures may affect clinical outcomes, and there is growing interest in understanding the clinical implications of surgeon proficiency levels.
Objectives: To determine whether surgeon scores representing technical skills of robot-assisted kidney surgery are associated with patient outcomes.
Design, Setting, And Participants: This quality improvement study included 10 urological surgeons participating in a surgical collaborative in Michigan from July 2021 to September 2022.
Purpose: To replicate a patient's internet search to evaluate ChatGPT's appropriateness in answering common patient questions about anterior cruciate ligament reconstruction compared with a Google web search.
Methods: A Google web search was performed by searching the term "anterior cruciate ligament reconstruction." The top 20 frequently asked questions and responses were recorded.
Campylobacter jejuni is a commensal in many animals but causes diarrhea in humans. Its polysaccharide capsule contributes to host colonization and virulence in a strain- and model-specific manner. We investigated if the capsule and its heptose are important for interactions of strain NCTC 11168 with various hosts and their innate immune defenses.
View Article and Find Full Text PDFArticle Synopsis
- Buprenorphine is an effective treatment for opioid use disorder but is often underused in emergency departments (EDs), prompting a study to assess how an initiative affects emergency physician knowledge and confidence.
- A survey conducted before and after the quality improvement (QI) initiative showed that physician confidence and knowledge about buprenorphine significantly increased, and more physicians began prescribing it post-initiative.
- Despite the increase in prescribing and confidence, attitudes and self-efficacy remained unchanged, with increased confidence linked to greater likelihood of prescribing buprenorphine.