Publications by authors named "M B M de Smet"
Background: Sudden cardiac death (SCD) is generally associated with life-threatening ventricular arrhythmias. Supraventricular arrhythmias are an accepted cause of SCD in Wolff-Parkinson-White syndrome and complex congenital heart disease. However, the role of atrial tachyarrhythmias (ATAs) in SCD in patients with structurally normal hearts is unclear.
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- - The survey, developed by the International Uveitis Study Group, aimed to assess how uveitis and retina specialists use current terminology and multimodal imaging (MMI) for diagnosing white dot syndromes (WDS).
- - Out of 432 initial respondents, 263 completed the survey, revealing that most participants specialize in uveitis and utilize MMI, with nearly 90% using it for WDS diagnosis but showing varied usage of the term WDS.
- - The findings suggest a strong consensus among specialists for redefining WDS based on anatomical location rather than the current clinical term, emphasizing MMI's role in enhancing diagnostic precision.
Atrial Topology for a Unified Understanding of Typical and Atypical Flutter.
Circ Arrhythm Electrophysiol
November 2024
Article Synopsis
- Macroreentry is the main cause of typical and atypical flutter, but many questions about it remain unanswered, prompting a study that uses topology to investigate atrial tachycardia activation patterns.
- Researchers utilized a computational model resembling a closed sphere with holes to analyze cases of tachycardia, focusing on activation maps and ablation responses in 131 clinical cases.
- The study's findings suggest that reentrant activity on closed surfaces consistently shows paired rotation, and through mathematical principles, they established a framework to better understand flutter and its treatment outcomes.
Ternary amorphous solid dispersions (ASDs) consist of a multicomponent carrier with the aim of improving physical stability or dissolution performance. A polymer blend as a carrier that combines a water-insoluble and a water-soluble polymer may delay the drug release rate, minimizing the risk of precipitation from the supersaturated state. Different microstructures of the ternary ASD may result in different drug release performances; hence, understanding the phase morphology of the polymer blend is crucial prior to drug incorporation.
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