Effect of Artemisia annua on anticoccidial action, intestinal microbiota and metabolites of Hu lambs.

Background: Coccidia are among the primary pathogens causing diarrhea and even fatalities in lambs. With the increasing use of chemical drugs to treat coccidiosis, the problem of drug resistance is becoming more and more threatening. Therefore, there is an urgent need to identify novel alternative drugs for the treatment of the lamb coccidia.

Temperature-driven CsgA-enhanced mutant enable distinct self-assembly.

Functional coating materials have found extensive applications across various technological fields. However, the effectiveness of these coating depends critically on the choice of an appropriate medium. In this study, we developed an advanced "molecular glue", a CsgA variant known as CsgA-pro, which can serve as a versatile medium for biotherapy.

Current progress and future perspectives in personal identification of monozygotic twins in forensic medicine.

The personal identification of monozygotic (MZ) twins is of great importance in forensic medicine. Due to the extreme similarity in genetic between MZ twins, it is challenging to differentiate them using autosomal STR genotyping. Forensic experts are striving to explore available genetic markers that can differentiate between MZ twins.

Declines in anthropogenic mercury emissions in the Global North and China offset by the Global South.

Human activities have emitted substantial mercury into the atmosphere, significantly impacting ecosystems and human health worldwide. Currently, consistent methodologies to evaluate long-term mercury emissions across countries and industries are scant, hindering efforts to prioritize emission controls. Here, we develop a high-spatiotemporal-resolution dataset to comprehensively analyze global anthropogenic mercury emission patterns.

Electroselective and Controlled Cross-Coupling of Isoindolinones with Alcohols.

A novel and efficient electrochemical method for electroselective and controlled cross-coupling of isoindolinones with equivalent alcohols has been developed without the need for metal catalysts and strong bases under mild conditions. The reaction provides a novel strategy for the controllable and effective synthesis of 3-alkoxyl and -hydroxymethyl-substituted isoindolinones, which is adjusted by 4-OH-TEMPO and tolerates various substrates. This protocol is an efficient tool for the construction of C-O and C-N bonds with high chemoselectivity.