Publications by authors named "M B Lande"

Article Synopsis
  • The study investigated the link between elevated systolic blood pressure (SBP) and neurocognitive performance in adolescents, focusing on measures like auscultatory SBP and ambulatory SBP, along with cardiovascular health risk indicators.
  • It involved 365 adolescents, averaging 15.5 years old, from various academic medical centers in the U.S., analyzing their cognitive abilities like nonverbal IQ and attention, considering factors like maternal education.
  • Results showed that higher SBP corresponded to lower nonverbal IQ and verbal attention scores, indicating that even slight elevations in blood pressure can negatively affect adolescent cognitive functions, suggesting a need for further research on these implications for clinical care.
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Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in adults, yet its underlying pathophysiology remains poorly understood. This study assessed whether circulating biomarker concentrations differ in paroxysmal AF patients during an acute episode compared to sinus rhythm.

Methods: The Time of Calamity study is a prospective biomarker study within the RACE V study.

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Background: Preventing high heart rates in patients with atrial fibrillation (AF) is a key objective of AF management. Data regarding heart rates in patients with paroxysmal AF (PAF) is lacking. This analysis aimed to provide insight into heart rates during PAF episodes measured with continuous implantable loop monitoring.

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Background: Obesity is associated with increased complications, rejection, and graft loss after kidney transplantation in adult and pediatric recipients. Elevated body mass index (BMI) is a common contraindication to transplant at adult kidney transplant programs; however, there is no data on such limitations for pediatric patients.

Methods: Between October and December 2022, we conducted a survey of Pediatric Nephrology Research Consortium centers assessing the use of BMI in pediatric kidney transplant evaluation.

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Article Synopsis
  • Primary hypertension in children can lead to increased cardiovascular risks as they grow into adults, making early studies crucial for understanding organ damage.
  • A study involving 132 youths showed significant correlations between blood pressure levels, gene expression, and molecular profiles, highlighting distinct biological changes in those with high blood pressure.
  • Findings suggest that mechanisms behind elevated blood pressure could involve issues with blood vessel growth and tissue breakdown, offering potential targets for intervention in preventing long-term cardiovascular damage.
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