[Syndrome of optic nerve atrophy, diabetes mellitus and diabetes insipidus].

The paper is concerned with a case of a familial variant of the hereditary De Lawter syndrome, optic nerve atrophy coupled with diabetes mellitus and insipidus. Double diabetes was detected in two brothers. Their uncle suffered from deaf-mutism.

[The myocardial contractile function and central hemodynamics of patients with insulin-dependent diabetes mellitus during treatment].

The results of echocardiographic investigation of 48 patients with type I diabetes mellitus (DM) were compared: 48 patients received routine therapy including diabetic management, insulin and vitamin therapy, 32 received this type of therapy plus a complex consisting of inosine, benphothiamine and pyridoxal phosphate. A considerable decrease in myocardial contractility and hemodynamic disorder were revealed against a background of DM decompensation in both groups of patients. Clinical improvement resulting from the use of the above complex showed good correlation with a positive course of echocardiographic values of myocardial contractility and pumping function.