Publications by authors named "M B Juul"
Background: Fecal Microbiota Transplant (FMT) is an effective treatment for recurring Clostridioides Difficile Infections (rCDI). FMT administered oral capsules (caFMT) offers several practical advantages to conventional liquid FMT. We began using caFMT in 2021 imported from an external institution.
View Article and Find Full Text PDFProgression of disease within 24 months (POD24) in follicular lymphoma in the rituximab era: incidence, clinicopathological risk factors, and outcome in a population-based Danish cohort.
Blood Cancer J
September 2024
Unlabelled: Stereoisomers are molecules that are identical in atomic constitution and bonding. The biological properties may, however, differ significantly between two enantiomers (individual stereoisomers). JBC 1847, a phenothiazine derivative with strong antimicrobial activity against Gram-positive bacteria, exists in two enantiomers, S and R.
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- EBV-associated T-cell and NK-cell lymphoproliferative diseases are rare and deadly, especially in Caucasians, with this study focusing on a 19-year-old boy diagnosed with systemic EBV positive T-cell lymphoma.
- The research highlights severe immune issues, including lympho-depletion and halted thymopoiesis, linked to heightened EBV and immune activation.
- A significant somatic missense variant in the proto-oncogene FYN was found, with a 48% variant allele frequency in this case, suggesting it may play a role in excessive T-cell activation and could be a potential target for future treatments.
Targeted alpha therapies (TAT) are an innovative class of therapies for cancer treatment. The unique mode-of-action of TATs is the induction of deleterious DNA double-strand breaks. Difficult-to-treat cancers, such as gynecologic cancers upregulating the chemoresistance P-glycoprotein (p-gp) and overexpressing the membrane protein mesothelin (MSLN), are promising targets for TATs.
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