The pre and intraoperative use of calcium channel blockers (CCB) has been suggested for the management of either eutopic or ectopic pheochromocytomas. We report our experience of 70 pheochromocytomas, operated between 1988 and 1996 and managed with CCB, especially nicardipine. 59 were hypertensive (84.
View Article and Find Full Text PDFThe perioperative mortality related to cardiovascular complications has been almost completely eliminated in phaeochromocytoma surgery. The anaesthetic management has mainly evolved through refinements in haemodynamic control during the operation. Neither preoperative preparation nor general anaesthesia can totally prevent haemodynamic disturbances during surgical manipulation of the tumour or after removal of the tumour.
View Article and Find Full Text PDF74 patients underwent surgery for organic hyperinsulinism (51 cases) or for Zollinger-Ellison syndrome (23 cases). 20 minutes after removal of the specimen, quick intra-operative hormone measurements were done in the systemic and portal blood as well, with intra-operative secretin stimulation test for gastrinoma(s), to assess completeness of surgery. Results accurately predicted cure (all insulinomas) or non-cure (half of gastrinomas) of the disease.
View Article and Find Full Text PDF