Esterase-2 mutant-based nanostructured amperometric biosensors for the selective determination of paraoxon (Neurotoxin).

Organophosphate pesticides (OPs) are causing non-selective inhibition in enzymatic bioreceptors, thus the enzymatic-inhibition-based traditional assays are not suitable for their specific detection in food and environmental samples. Accordingly, a selective nanostructured electrochemical biosensing system was designed using six mutants of the esterase-2 (EST2 protein) enzymes from A. acidocaldarius to be exploited as targeting bio-receptors for the specific detection of OPs.

Optimizing resource utilization for large scale problems through architecture aware scheduling.

Rapid development realms of parallel architectures and its heterogeneity have inspired researchers to invent new scheduling strategies to efficiently distribute workloads among these architectures in a way that may lead to better performance. This paper presents a comprehensive study on optimizing resource utilization for large-scale problems by employing architecture-aware scheduling techniques. We conducted a series of experiments to measure the execution times of various architectures with different problem sizes.

Comparative study of Saudi and Turkish coffee consumption in Saudi Arabia: insights into sociodemographic factors and caffeine intake.

Background: Saudi and Turkish coffee consumption in Saudi Arabia is increasing considerably, and the nationwide consumption patterns need elucidation to determine the contributions of Saudi and Turkish coffee toward nutrition and health.

Aim: To describe the frequency and quantity of Saudi and Turkish coffee consumption and assess their association with sociodemographic factors.

Methods: This cross-sectional study included 1,030 participants (Saudi Arabia) recruited via an online questionnaire study that collected information on general characteristics and coffee consumption.

Exploring oxidative stress, immunological and metabolic biomarkers in dairy cows with postpartum pyometra.

Pyometra is a prevalent and severe infectious disease that affects the reproductive systems of cattle worldwide. This study's main goal was to investigate the biomarkers for oxidative stress (OS), adiponectin, leptin and neopterin (NPT) in cows suffering from postpartum pyometra. The study also aimed to determine which bacteria were most commonly implicated in the development of the disease.

Epidemiological insights into paratuberculosis in camels in Saudi Arabia: Bayesian estimation of true prevalence and identification of risk factors.

Paratuberculosis, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a significant concern in the camel population of Saudi Arabia. This study aimed to provide epidemiological insights into the disease by estimating the true prevalence in camels in the Eastern Province and Riyadh, using a Bayesian estimation framework, and exploring the associated risk factors through a frequentist approach.