One Size Fits Small: The Narrow Utility for Plasma Metagenomics.

Metagenomic sequencing of plasma has been advertised by Karius, Inc. as a way to diagnose a variety of infectious syndromes. Due to the lack of robust evidence of clinical utility, our laboratory began actively stewarding Karius testing.

Professor Dr. Shuying Liu (1943.1-2023.11): A Devoted Mass Spectrometrist and Esteemed Mentor.

A year has gone by, and it is still hard to believe that Dr. Shuying Liu had left us on November 22, 2023. Most her colleagues and friends remember vividly her passionate images captured in the talk she filmed for the Chinese Mass Spectrometry Conference 2020-2023 in June 2023.

Nutritional interventions in randomised clinical trials for people with incurable solid cancer: A systematic review.

Background & Aims: Malnutrition is highly prevalent in those with cancer and more so in those with incurable cancer. In incurable cancer, it is widely agreed that optimal nutritional care has the potential to positively impact patient and caregiver distress and oncological outcomes. The aim of this systematic review was to describe the diversity and frequency of nutritional interventions, whether given in isolation or as part of a multimodal intervention in those with incurable cancer, in randomised controlled trials.

Implementing and evaluating shared decision-making before transcatheter aortic valve implantation with a dedicated pathway and questionnaire.

Aims: Transcatheter aortic valve implantation (TAVI) is an alternative to surgical aortic valve replacement for patients with aortic valve stenosis. The choice between TAVI, surgery, or a conservative approach should be based upon multiple factors including clinical considerations, technical feasibility, and informed patient preference. In this context, engaging patients in a shared decision-making (SDM) process becomes essential, but this practice is generally underused.

Should We Operate on Octogenarians with Cervical Myelopathy or Radiculopathy?

Study Design: Retrospective Cohort.

Objective: Investigate the disparities between octogenarians and non-octogenarians undergoing cervical spine surgery regarding perioperative, and postoperative outcomes.

Summary Of Background Data: As the population ages, the demand for elective cervical spine surgery among older, more active adults increases.