Use of a recombinant human follicle-stimulating hormone:recombinant human luteinizing hormone (r-hFSH:r-hLH) 2:1 combination for controlled ovarian stimulation during assisted reproductive technology treatment: A real-world study of routine practice in the Russian Federation.

Two observational studies in the Russian Federation described patient demographics/clinical decision for treatment with recombinant human follicle-stimulating hormone:recombinant human luteinizing hormone (r-hFSH:r-hLH) 2:1 combination for ovarian stimulation (OS) during assisted reproductive technology (ART) and outcomes, respectively. The first (prospective) study enrolled 500 patients. After post-hoc regrouping to assign patients to discrete groups, 378 (75.

Priming with a gonadotropin-releasing hormone agonist before immature oocyte retrieval may improve maturity of oocytes and outcome in in vitro maturation (IVM) cycle: a case report.

Background: The concept of using a gonadotropin-releasing hormone agonist (GnRH-a) instead of human chorionic gonadotropin for triggering ovulation in patients treated with an antagonist protocol for in vitro fertilization (IVF) has become a routine clinical practice. It may promote oocyte nuclear maturation, resumption of meiosis and cumulus expansion. It seems that this attempt could be beneficial in an in vitro maturation (IVM) oocyte cycle performed for polycystic ovarian syndrome as well as for other indications such as urgent fertility preservation in patients with malignancies or unusual indications.

[Pregnancy after transfer of the gametes into the fallopian tubes].

Three patients with idiopathic sterility were treated by transferring the gametes into uterine tubes. Clomiphene+ citrate stimulation of superovulation was employed. Preovulatory oocytes were obtained via the laparoscopic approach.

[Evaluation of ovarian response in ovulation induction].

To decrease the cost of determining estrogens by the High Estrotex (Mochida Pharmaceutica, Japan) method, the authors have modified it, thus reducing the usage of expensive reagents four times. The modified method was applied to evaluate estrogens in 27 infertile patients when stimulating superovulation. The findings were in agreement with the results obtained by foreign special clinics engaged in treating infertility with extracorporeal fertilization followed by embryonal transfer.

[Results of the treatment of infertility by the method of extracorporeal fertilization].

Outpatient in vitro insemination has been performed in 609 infertile couples in 1145 menstrual cycles. Age of the women ranged from 19 to 44 years and their history of infertility, from 2 to 17 years. Tubal infertility was present in 439 patients and one or both tubes were patent in 170 patients.