Publications by authors named "M B Alexander"
Background: Canada and the United States are both aging and becoming increasingly diverse. Despite this demographic shift, non-White racial/ethnic groups remain underrepresented in research on cognitive impairment and dementia. A major barrier to inclusivity is the lack of cognitive assessments that are valid in individuals with diverse language and cultural backgrounds.
View Article and Find Full Text PDFBackground: Despite being among the fastest-growing ethnoracial groups in Canada and the United States, individuals of Asian descent are significantly underrepresented in research on Alzheimer's disease and related dementias (ADRD). Limited evidence suggests a lower incidence of dementia among Asian Americans compared to their White counterparts; however, there is variability in risk factors among Asian American subgroups. Understanding this heterogeneity is crucial for tailoring dementia prevention and intervention strategies in Asian populations.
View Article and Find Full Text PDFDiscordance of 3rd and 4th generation QuantiFERON-TB Gold assays by pregnancy stages in India.
J Clin Tuberc Other Mycobact Dis
February 2025
Background: Pregnancy and HIV affect CD4+ T lymphocytes and impact performance of QuantiFERON-TB Gold (QFT). We compared the results of QFT with QuantiFERON-TB Gold Plus (QFT-Plus), which also measures CD8+ responses to TB antigens, during pregnancy and postpartum.
Methods: We screened 516 pregnant women for TB infection (TBI) with IGRA.
Article Synopsis
- The study investigates CP symmetry violation in the decay of D^{+} particles into K^{-}K^{+}π^{+} using data from proton-proton collisions at a high energy of 13 TeV.
- A unique model-independent method was employed to analyze the phase-space distributions of D^{+} and D^{-} particles, correcting for any instrumental biases using D_{s}^{+} decays.
- The findings indicate no significant evidence of CP violation, with a p value of 8.1%, and measure specific CP asymmetry observables, marking this study as the most sensitive search of its kind in multibody decays.
Background: Change in the oxygen consumption (VO) at the ventilatory anaerobic threshold (VAT) is an important outcome in research studies of children with congenital heart disease (CHD). The range of values reported by different raters for any given VAT is needed to contextualize a change in VAT in intervention studies.
Methods: Sixty maximal cardiopulmonary exercise tests (CPET) for CHD patients 8-21 years old were independently reviewed by six exercise physiologists and four pediatric cardiologists.