Publications by authors named "M Atienza"

Path integration (PI), which supports navigation without external spatial cues, is facilitated by grid cells in the entorhinal cortex. These cells are often impaired in individuals at risk for Alzheimer's disease (AD). However, other brain systems can compensate for this impairment, especially when spatial cues are available.

View Article and Find Full Text PDF
Article Synopsis
  • A study was conducted to explore the link between insulin resistance (IR) and the progression from mild cognitive impairment (MCI) to Alzheimer's disease (AD) dementia in a group of 400 subjects.
  • Researchers identified a specific metabolic signature with 18 metabolites that are associated with IR and showed that this signature increases the risk of developing AD dementia.
  • The findings suggest that these metabolic pathways could help explain how IR contributes to the development of AD dementia, enhancing our understanding of this relationship.
View Article and Find Full Text PDF
Article Synopsis
  • Psychodermatology examines the link between skin conditions and mental health, highlighting the need for dermatologists to understand the psychological aspects of skin diseases.
  • A study with 153 Filipino dermatologists found that while many are comfortable with psychodermatology, only a third have sufficient knowledge on the subject, and most encounter more secondary psychiatric disorders than primary ones.
  • Despite challenges, the majority of participants recognize the importance of psychodermatology and are open to further education in this area, with many having attended Continuing Medical Education sessions on the topic.
View Article and Find Full Text PDF

Background: Dermoscopy enhances detection of basal cell carcinoma (BCC), especially for the pigmented subtype common among Asians. However, there is limited data on dermoscopic features of BCC in Filipinos.

Objectives: The objective of this study is to describe the clinicopathologic profile and dermoscopic features of BCC in Filipinos seen in a tertiary care clinic.

View Article and Find Full Text PDF

This real-world study aimed to describe patient and clinical characteristics, treatment patterns and outcomes for patients with HR+/HER2- metastatic breast cancer receiving abemaciclib in France, Italy and Spain. A multicenter chart review was conducted for adult females with HR+/HER2- advanced/metastatic breast cancer who received abemaciclib in routine care. Real-world progression-free survival (rwPFS) was estimated via Kaplan-Meier curves.

View Article and Find Full Text PDF