Publications by authors named "M Ashwini"
Rabies is a fatal, acute progressive encephalomyelitis caused by the rabies virus and other Lyssaviruses. Several other clinical conditions can mimic rabies. Antemortem laboratory diagnosis remains challenging and requires multiple or serial sampling for confirmation.
View Article and Find Full Text PDFCardiovascular diseases (CVD) are a predominant health concern globally, emphasizing the need for advanced diagnostic techniques. In our research, we present an avant-garde methodology that synergistically integrates ECG readings and retinal fundus images to facilitate the early disease tagging as well as triaging of the CVDs in the order of disease priority. Recognizing the intricate vascular network of the retina as a reflection of the cardiovascular system, alongwith the dynamic cardiac insights from ECG, we sought to provide a holistic diagnostic perspective.
View Article and Find Full Text PDFBackground: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder that imposes significant complications, including diabetic peripheral neuropathy (DPN). DPN is characterized by marked inflammation, and the fibrinogen-to-albumin ratio (FAR) is one of the new markers for systemic inflammation, it has been used in various diabetic micro- and macro-vascular complications. The present study investigates the association between FAR and nerve conduction abnormalities in T2DM patients with DPN.
View Article and Find Full Text PDFObjectives: The objective of this study was to achieve integration of goals of care discussion (GOCD) as a routine part of assessment among seriously ill patients admitted to medical wards and assess its impact on patient satisfaction, caregiver satisfaction and quality of life (QOL).
Materials And Methods: This was non-randomised before and after study - A quality improvement project involving three plan-do-study-act (PDSA) cycles each of 6 weeks duration. The study included a total of 60 patients and their caregivers admitted to the Internal Medicine Unit in a tertiary care hospital in South India.
Integrating one health strategies for rabies control: Insights from Jackal-mediated human rabies in Northeast India.
Comp Immunol Microbiol Infect Dis
January 2025
Article Synopsis
- Rabies is a deadly disease caused by Lyssavirus, primarily transmitted to humans through domestic dogs, but wildlife like jackals also play a role, as shown in a case from India.
- RNA from a rabid jackal and a human victim was analyzed using real-time PCR and whole genome sequencing to understand the virus's characteristics.
- Results indicated that both the jackal and human carried rabies virus from the Arctic AL1a lineage, suggesting a connection to dog strains in the region, emphasizing the need for improved rabies control measures.